MOLECULAR WINNOWING, EXPRESSIONAL ANALYSES AND INTERACTOME SCRUTINY OF CELLULAR PROTEOMES OF ORAL SQUAMOUS CELL CARCINOMA

Molecular winnowing, expressional analyses and interactome scrutiny of cellular proteomes of oral squamous cell carcinoma

Background: Oral cancer is one of the highly aggravated conditions of oral pathologies.The commonly diagnosed form of oral cancer is oral squamous cell carcinoma (OSCC).The molecular players responsible for low post-treatment cancer-free survival rate and higher recurrence & metastasis rates associated with OSCC are still obscure.This study aim

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Lead level in mallard (Anas platyrhynchos)

The study was carried out on a hunting ground belonging to AJVPS Arad, county Arad.Lead (Pb) was determined in Mallard (Anas platyrhynchos) tissues (muscles) and organs (liver, kidneys) to see the contamination level of this tissues and organs and also the impact on humans health because in silver lining herbs kidney support our days more and more

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Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

Abstract Background Glioblastoma (GBM), a malignant brain tumor, has poor survival outcomes due to recurrence or drug resistance.We found that SH3GLB1 is a crucial factor for cells to evade temozolomide (TMZ) cytotoxicity through autophagy-mediated oxidative phosphorylation, which is associated with CD133 levels.Therefore, we propose sofia barclay

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EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses

Abstract Aberrant N-glycosylation has been implicated in viral diseases.Alpha-(1,6)-fucosyltransferase (FUT8) is the sole enzyme responsible for core fucosylation of N-glycans during glycoprotein biosynthesis.Here we find that multiple viral envelope proteins, including Hepatitis C Virus (HCV)-E2, Vesicular stomatitis virus (VSV)-G, Severe acute re

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